Dr. Joseph NDACYAYISENGA has been working at INES Ruhengeri since 2015, initially as a part-time assistant lecturer in the Department of Biotechnologies. In 2016, he transitioned to a full-time role as an assistant lecturer and lab analyst in the Molecular Biology Laboratory within the same department, and in 2024, he was promoted to the position of lecturer. He holds a PhD in Molecular Biology and Biotechnology from the Pan African University - Institute of Basic Sciences, Technology and Innovation (PAUSTI) and Jomo Kenyatta University of Agriculture and Technology (JKUAT).

Dr. Joseph has acquired various professional and short course certifications, including a short course in Molecular Data for Infectious Diseases (MID) from the Institute of Tropical Medicine (ITM), Belgium; RS ISO/IEC 17025:2005 General Competence of Testing and Calibration Laboratories; ISO 15189:2012 Medical Laboratories - Requirements for Quality and Competence; ISO/IEC 17043:2010 Accredited Proficiency Testing Program; JUNCAO Technology (Mushroom Culture and Production); Laboratory Management; and Laboratory Animal Use and Handling, among others.

He is highly skilled in advanced molecular biology and biotechnology-related techniques such as Next-Generation Sequencing (NGS), Real-Time PCR, RT-PCR, animal cell culture techniques, laboratory animal use and handling,  HPLC, etc. Dr. Joseph has published numerous research papers in international scientific journals with significant impact factors and citations.

Some notable publications include:

[1]      Ndacyayisenga J, Maina E, Ngeny L, Wamunyokoli F, Tolo F. Purple tea catechins exhibit high antiproliferative activity and synergism with cisplatin against the triple-negative breast cancer cell line 4T1. Arch Biol Sci 2023;75:475–88. https://doi.org/10.2298/ABS230816039N.

[2]      Ndacyayisenga J, Tolo FM, Wamunyokoli F, Maina EN. Effects of tea catechin extracts from BB35 and purple (TRFK 306) tea clones on the gene expression of Egfr, App, Bcl2, Dnmt, Casp3, Hif1a, Gadd45b and Psmb5 genes involved in triple negative breast cancer diseases: In silico and in vitro study. Informatics Med Unlocked 2024;46:101469. https://doi.org/10.1016/j.imu.2024.101469.

[3]      Uwanyagasani G, Song’oro E, Ndacyayisenga J, Terefe EM, Muriuki J. In vitro activity of various Kenyan tea extracts against HeLa human cervical cancer cell line and molecular docking of tea catechins on high-risk HPV16E6 protein. Informatics Med Unlocked 2024;44:101420. https://doi.org/10.1016/j.imu.2023.101420.

[4]      Ndacyayisenga J, Izabayo Ihirwe A, Innocent H, Celise DA. Assessment of microbiological quality of raw milk produced and commercialised around INES Ruhengeri, Musanze district, Rwanda. African J Biol Sci 2021;3:114. https://doi.org/10.33472/AFJBS.3.4.2021.114-123.

[5]      Ndacayisenga J., Anbazhagan, M., & Srinivasan S. In vitro growth of potato plant (in vitro tuberization). Int J Curr Sci 2015:17, 29-36.

[6]      Yumukjije C. & Ndacyayisenga J, Phytochemical analysis & in vitro anticancer activity of methanol extract of Catharanthus Roseus leaves using HEPG2 cell line. IAETSD J Adv Res Appl Sci Vi 2019:2394–8442.

[7]      Ndacyayisenga J, Muriuki J, Uwanyagasani G, Maina E, Irungu B, Khamadi S, Lwembe R, Adan A, Barmasai S. Assessing the antiproliferative properties of various teas against the DU-145 prostate cancer cell line: A combined in vitro and in silico investigation. Phytomedicine Plus 2024;4:100667. https://doi.org/10.1016/j.phyplu.2024.100667.

[8]      Munezero PC, Mukiza P, Mutijima JB, Kankindi J, Nshimiyimana A, Ishimwe AP, Tuyishime JD, Sinumvayo JP, Ndayambaje FX, Ndacyayisenga J. Assessment of rheumatoid arthritis and associated risk factors among patients attending Kibungo level two teaching hospital. J Drug Deliv Ther 2023;13:119–24. https://doi.org/10.22270/jddt.v13i9.5962.

[9]      Munezero PC, Handunnetti S, Fernando N, Ranaweera L, Hapuarachchi SD, Nyamweya BM, Ndacyayisenga J. Preliminary study on the effect of Munronia pinnata (Wall) Theob. (Meliaceae) aqueous extract on functional change in endothelial cells infected by dengue virus. Sci African 2023;21:e01861. https://doi.org/10.1016/j.sciaf.2023.e01861.

[10]    Munezero PC, Usengimana A, Mutijima JB, Yamukujije C, Ndacyayisenga J,  Sinumvayo JP, Ndayambaje FX, Nshimiyimana A. Helicobacter pylori Infection in Association with Iron Deficiency Anemia in Adults at Legacy Clinics, in Rwanda: A Clinic based Cross-Sectional Study. Int J Pharma Res Heal Sci 2023;11:3655–60.

 Email: jndacyayisenga@ines.ac.rw  phone:  +250788613762.